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Get Free AccessBrain alterations associated with specific phobia exceeded those of other anxiety disorders in comparable analyses in extent and effect size and were not limited to reductions in brain structure. Moreover, phenomenological differences between phobia subgroups were reflected in diverging neural underpinnings, including brain areas related to fear processing and higher cognitive processes. The findings implicate brain structure alterations in specific phobia, although subcortical alterations in particular may also relate to broader internalizing psychopathology.
Kevin Hilbert, Ole Jonas Boeken, Till Langhammer, Nynke A. Groenewold, Janna Marie Bas‐Hoogendam, Moji Aghajani, André Zugman, Fredrik Åhs, Volker Arolt, Katja Beesdo‐Baum, Johannes Björkstrand, Jennifer Urbano Blackford, Laura Blanco‐Hinojo, Joscha Böhnlein, Robin Bülow, Marta Cano, Narcı́s Cardoner, Xavier Caseras, Udo Dannlowski, Katharina Domschke, Lydia Fehm, Brandee Feola, Mats Fredrikson, Liesbet Goossens, Hans J. Grabe, Dominik Grotegerd, Raquel E. Gur, Alfons O. Hamm, Anita Harrewijn, Ingmar Heinig, Martin J. Herrmann, David Hofmann, Andrea Parolin Jackowski, Andreas Jansen, Antonia N. Kaczkurkin, Merel Kindt, Ellen Kingsley, Tilo Kircher, Anna Luisa Klahn, Katja Koelkebeck, Axel Krug, Harald Kugel, Bart Larsen, Elisabeth J. Leehr, Lieselotte Leonhardt, Martín Lotze, Jürgen Margraf, Jarosław M. Michałowski, Markus Muehlhan, Igor Nenadić, Pedro Mário Pan, Paul Pauli, Wenceslao Peñate Castro, Andre Pittig, Jens Plag, Jesús Pujol, Jan Richter, Francisco Rivero, Giovanni Abrahão Salum, Theodore D. Satterthwaite, Axel Schäfer, Judith Schäfer, Anne Schienle, Silvia Schneider, Elisabeth Schrammen, Koen Schruers, Stefan M. Schulz, Esther Seidl, Rudolf Stark, Frederike Stein, Benjamin Straube, Thomas Straube, Andreas Ströhle, Boris Suchan, Sophia I. Thomopoulos, Carlos Ventura‐Bort, Renée M. Visser, Henry Völzke, Albert Wabnegger, André Wannemüller, Julia Wendt, Julian Wiemer, Hans‐Ulrich Wïttchen, Katharina Wittfeld, Barry Wright, Yunbo Yang, Anna Zilverstand, Peter Zwanzger, Dick J. Veltman, Anderson M. Winkler, Daniel S. Pine, Neda Jahanshad, Paul M. Thompson, Dan Joseph Stein, Nic J. A. van der Wee, Ulrike Lueken (2024). Cortical and Subcortical Brain Alterations in Specific Phobia and Its Animal and Blood-Injection-Injury Subtypes: A Mega-Analysis From the ENIGMA Anxiety Working Group. , 181(8), DOI: https://doi.org/10.1176/appi.ajp.20230032.
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Type
Article
Year
2024
Authors
96
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1176/appi.ajp.20230032
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