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Get Free AccessAmong patients with atrial fibrillation at risk for stroke, treatment with asundexian at a dose of 50 mg once daily was associated with a higher incidence of stroke or systemic embolism than treatment with apixaban in the period before the trial was stopped prematurely. There were fewer major bleeding events with asundexian than with apixaban during this time. (Funded by Bayer; OCEANIC-AF ClinicalTrials.gov number, NCT05643573; EudraCT number, 2022-000758-28.).
Jonathan P. Piccini, Manesh R. Patel, Jan Steffel, Keith C. Ferdinand, Isabelle C. Van Gelder, Andrea M. Russo, Chang-Sheng Ma, Shaun G. Goodman, Jonas Oldgren, Christopher Hammett, Renato D. Lópes, Masaharu Akao, Raffaele De Caterina, Paulus Kirchhof, Diana A. Gorog, Martin E W Hemels, Michiel Rienstra, W. Schuyler Jones, Josephine Harrington, Professor Gregory Lip, Stephen J. Ellis, Frank W. Rockhold, Christoph Neumann, John H. Alexander, Thomas Viethen, James Hung, Rosa Coppolecchia, Hardi Mundl, Valeria Caso (2024). Asundexian versus Apixaban in Patients with Atrial Fibrillation. , 392(1), DOI: https://doi.org/10.1056/nejmoa2407105.
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Type
Article
Year
2024
Authors
29
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1056/nejmoa2407105
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