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Get Free AccessLIPI is a significant independent prognostic marker for DCR in patients with STS treated with immunotherapy. In early-phase trials, LIPI could be used as a screening tool for stratification at inclusion. High neutrophil levels, which correlate with a poorer LIPI score, are likely associated with immunotherapy resistance. This relationship could explain the statistical impact of poor LIPI in the immunotherapy group.
Marianne Zoghbi, Bharti Patel, Matthieu Roulleaux Dugage, Laura Mezquita, Rastilav Bahleda, Armelle Dufresne, Mehdi Brahmi, Isabelle Ray‐Coquard, Patricia Pautier, Jean Yves Blay, Axel Le Cesne, Christophe Massard, Benjamin Besse, Édouard Auclin, Elise F. Nassif (2024). Association of Lung Immune Prognostic Index (LIPI) with Disease Control Rate and Progression-Free Survival in Patients with Soft-Tissue Sarcoma Treated with Immunotherapy in Early-Phase Trials. , 16(23), DOI: https://doi.org/10.3390/cancers16234053.
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Type
Article
Year
2024
Authors
15
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.3390/cancers16234053
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