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Get Free AccessFabrication of low-cost biosensing platforms with high selectivity and sensitivity is important for constructing portable devices for personal health monitoring. Herein, we report a simple biosensing strategy based on the combination of a cationic AIEgen (aggregation-induced emission fluorogen), TPE-2+, with an aptamer for specific protein detection. The target protein can displace the dye molecules on the dye–aptamer complex, resulting in changes in the fluorescence signal. Selectivity towards different targets can be achieved by simply changing the aptamer sequence. The working mechanism is also investigated.
Tracey Luu, Mengjie Liu, Yilong Chen, Roozbeh Hushiarian, Anthony E. G. Cass, Ben Zhong Tang, Yuning Hong (2019). Aptamer-Based Biosensing with a Cationic AIEgen*. , 72(8), DOI: https://doi.org/10.1071/ch19238.
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Type
Article
Year
2019
Authors
7
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1071/ch19238
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