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Get Free AccessBackground. Extent of neck dissection is controversial in patients with palpable medullary thyroid cancer (MTC). Methods. We evaluated 64 MTC patients (19 hereditary, 45 sporadic) with palpable thyroid nodules (group 1, n = 35) or palpable lymph node metastases (group 2, In = 29). Standard surgery included total thyroidectomy, central compartment dissection, and additional neck dissection on indication. Results. In group 1, 40% of the patients were cured. Thirty-one percent of all patients had central, 23% ipsilateral, 14% contralateral, and 14% mediastinal, metastases. Fifty-one percent developed locoregional recurrence. Locoregional recurrence (p =.043) and reoperations (p =.020) were noted more often after a less than standard initial procedure, In group 2, no patients were cured, All had central, 93% ipsilateral, 45% contralateral, and 52% mediastinal metastases. Thirty-eight percent developed locoregional recurrence. Conclusions. Locoregional recurrence frequently occurs in palpable MTC, and tumor control may be improved by standard central, bilateral, and upper mediastinal neck dissection. (c) 2007 Wiley Periodicals, Inc.
Emanuele Leoncini, Walter Ricciardi, Gabriella Cadoni, Dario Arzani, L. Petrelli, Gaetano Paludetti, Patrick M. Brennan, Danièle Luce, Isabelle Stücker, Keitaro Matsuo, Renato Talamini, Carlo La Vecchia, Andy Olshan, D.M. Winn, Rolando Herrero, Silvia Franceschi, Xavier Castellsagué, Joshua Muscat, Hal Morgenstern, Zuo‐Feng Zhang, Fabio Levi, Luigino Dal Maso, Karl T. Kelsey, Michael D. McClean, T.L. Vaughan, P. Lazarus, Mark P. Purdue, Richard B. Hayes, C. Chen, Steven M. Schwartz, Oxana Shangina, Sérgio Koifman, Wolfgang Ahrens, Érica Naomi Naka Matos, Παγώνα Λάγιου, Jolanta Lissowska, N. Szeszenia-Dabrowska, L. Fernández, Ana Maria Baptista Menezes, Antonio Agudo, Alexander W. Daudt, Lorenzo Richiardi, Kristina Kjærheim, Dana Mateș, Jaroslav Betka, Guanhua Yu, Stimson Schantz, Lorenzo Simonato, Hermann Brenner, David I. Conway, Tatiana V. Macfarlane, Peter Thomson, Eleonora Fabianova, Ariana Znaor, P. Rudnai, Claire M. Healy, Paolo Boffetta, Shu‐Chun Chuang, Y. C. Lee, Mia Hashibe, Stefania Boccia (2014). Adult height and head and neck cancer: A pooled analysis within the INHANCE Consortium. , 36(10), DOI: https://doi.org/10.1002/hed.
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Type
Article
Year
2014
Authors
61
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1002/hed
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