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  5. A Brain‐Targeting NIR‐II Ferroptosis System: Effective Visualization and Oncotherapy for Orthotopic Glioblastoma (Adv. Sci. 13/2023)

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Article
en
2023

A Brain‐Targeting NIR‐II Ferroptosis System: Effective Visualization and Oncotherapy for Orthotopic Glioblastoma (Adv. Sci. 13/2023)

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en
2023
Vol 10 (13)
Vol. 10
DOI: 10.1002/advs.202370080

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Ben Zhong Tang
Ben Zhong Tang

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Jing Zhang
Lulu Han
Haigang Wu
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Abstract

Near‐Infrared Aggregation‐Induced Emission Ferroptosis Molecule A near‐infrared (NIR) aggregation‐induced emission ferroptosis molecule (TBTP‐Au) is first designed by introducing Au(I) active center. The self‐assembled TBTP‐Au nanoparticles with targeted modification display superior NIR imaging performance to monitor the blood‐brain barrier penetration of nanoparticles. The controlled release of TBTP‐Au specifically activate the effective heme oxygenase‐1‐regulated ferroptosis to greatly prolong the survival of glioma‐bearing mice. More details can be found in article number 2206333 by Jiefei Wang, Lei Zheng, Bingyang Shi, Ben Zhong Tang, and co‐workers. [Image: see text]

How to cite this publication

Jing Zhang, Lulu Han, Haigang Wu, Yong Zhong, Ping Shangguan, Yi‐Sheng Liu, Mu He, Han Sun, Chenhui Song, Xin Wang, Yang Liu, Jiefei Wang, Lei Zheng, Bingyang Shi, Ben Zhong Tang (2023). A Brain‐Targeting NIR‐II Ferroptosis System: Effective Visualization and Oncotherapy for Orthotopic Glioblastoma (Adv. Sci. 13/2023). , 10(13), DOI: https://doi.org/10.1002/advs.202370080.

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Publication Details

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Article

Year

2023

Authors

15

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0

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Language

en

DOI

https://doi.org/10.1002/advs.202370080

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